hydrochloride hydrate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9251	Fedratinib hydrochloride hydrate	TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate	Apoptosis , JAK
	Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.		Apoptosis , JAK
T2593	Eflornithine hydrochloride hydrate	Difluoromethylornithine hydrochloride hydrate,α-difluoromethylornithine hydrochloride hydrate,Eflornithine hydrochloride,MDL-71782 hydrochloride hydrate,DFMO hydrochloride hydrate,RMI-71782 hydrochloride hydrate,Eflornithine hydrochloride Monohydrate	Decarboxylase
	Eflornithine hydrochloride hydrate (RMI-71782 hydrochloride hydrate) is a specific, irreversible inhibitor of ornithine decarboxylase.		Decarboxylase
TQ0304	Metixene hydrochloride hydrate		AChR
	Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene hyd...		AChR
T8404	Kasugamycin hydrochloride hydrate	Ksg (hydrochloride hydrate)	Antibacterial , Antibiotic
	Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate))(Ksg) specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. Ksg inhibition is thought to occur by direct competitio...		Antibacterial , Antibiotic
T2191	Tacrine hydrochloride (hydrate)	Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine	AChR , AChE
	Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i...		AChR , AChE
T0038	Doxapram hydrochloride hydrate	Doxapram hydrochloride monohydrate,Doxapram HCl	Potassium Channel
	Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 values of 410 nM, 37 μM, and 9 μM, respectively.		Potassium Channel
T1144L	Lidocaine Hydrochloride hydrate		EGFR , Sodium Channel
	Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.		EGFR , Sodium Channel
TN5283	L-Cysteine hydrochloride hydrate	L-Cysteine hydrochloride monohydrate	Others , Endogenous Metabolite
	L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), taurine and gl...		Others , Endogenous Metabolite
T4990	Cefcapene pivoxil hydrochloride hydrate	Cefcapene Pivoxil Hydrochloride	Antibacterial , Antibiotic
	Cefcapene pivoxil hydrochloride hydrate is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil, the es...		Antibacterial , Antibiotic
T8385	Metoclopramide hydrochloride hydrate	Metoclopramide monohydrochloride monohydrate	Dopamine Receptor , 5-HT Receptor
	Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic		Dopamine Receptor , 5-HT Receptor
T35567	BIX01294 (hydrochloride hydrate)
	The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3)...
T38323	A-943931 (hydrochloride hydrate)
	A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.). 1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification...
T69002	Zimeldine hydrochloride hydrate
	Zimeldine hydrochloride hydrate is a serotonin uptake inhibitor that was formerly used for depression but was withdrawn worldwide in September 1983 because of the risk of Guillain-Barre Syndrome associated with its use.
T39864	CDK7-IN-2 hydrochloride hydrate	CDK7-IN-2 hydrochloride hydrate
	CDK7-IN-2 hydrochloride hydrate (Example 6) is a highly effective and specific inhibitor of the CDK7 enzyme. This compound exhibits significant anti-cancer properties.
T5081	Adenine monohydrochloride hemihydrate	Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate	Endogenous Metabolite , Adenosine Receptor
	Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor a...		Endogenous Metabolite , Adenosine Receptor
T36779	NG 25 (hydrochloride hydrate)
	NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinase...
T63505	Tivozanib hydrochloride hydrate
	Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hy...
T81445	PKRA83 hydrochloride hydrate	PKRA7 hydrochloride hydrate
	PKRA83 hydrochloride hydrate, also known as PKRA7, is a potent prokineticin (PK2) antagonist that competes with PK2 for binding to its receptors, PKR1 and PKR2. It exhibits high inhibitory affinity with IC50 values of 5....
T1235	Lincomycin hydrochloride monohydrate	Lincomycin hydrochloride hydrate	ribosome , Antibacterial , Antibiotic
	Lincomycin hydrochloride monohydrate (Lincomycin hydrochloride hydrate) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Ba...		ribosome , Antibacterial , Antibiotic
T13413	Zoniporide hydrochloride hydrate	CP-597396 hydrochloride hydrate	Others
	Zoniporide hydrochloride hydrate is a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor. Zoniporide hydrochloride hydrate inhibits human NHE-1 with IC50 of 14 nM.		Others